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Health for: Drug Guideprovided by: Healthwise ================================= AA-Ag Ah-Ap Aq-AzBB-Bg Bh-Bp Bq-BzCC-Cg Ch-Cp Cq-CzDD-Dg Dh-Dp Dq-DzEE-Eg Eh-Ep Eq-EzFF-Fg Fh-Fp Fq-FzGG-Gg Gh-Gp Gq-GzHH-Hg Hh-Hp Hq-HzII-Ig Ih-Ip Iq-IzJJ-Jg Jh-Jp Jq-JzKK-Kg Kh-Kp Kq-KzLL-Lg Lh-Lp Lq-LzMM-Mg Mh-Mp Mq-MzNN-Ng Nh-Np Nq-NzOO-Og Oh-Op Oq-OzPP-Pg Ph-Pp Pq-PzQQ-Qg Qh-Qp Qq-QzRR-Rg Rh-Rp Rq-RzSS-Sg Sh-Sp Sq-SzTT-Tg Th-Tp Tq-TzUU-Ug Uh-Up Uq-UzVV-Vg Vh-Vp Vq-VzWW-Wg Wh-Wp Wq-WzXX-Xg Xh-Xp Xq-XzYY-Yg Yh-Yp Yq-YzZZ-Zg Zh-Zp Zq-Zz0-90-2 3-6 7-9 Acetaminophen/butalbital/caffeine/codeine ========================================= Pronunciation: a seet a MIN o fen/byoo TAL bi tall/CAF een/KOE deenBrand Names: Fioricet with Codeine * Drug Details * What is the most important information I should know about acetaminophen/butalbital/caffeine/codeine? * What is acetaminophen/butalbital/caffeine/codeine? * Who should not take acetaminophen/butalbital/caffeine/codeine? * How should I take acetaminophen/butalbital/caffeine/codeine? * What happens if I miss a dose? * What happens if I overdose? * What should I avoid while taking acetaminophen/butalbital/caffeine/codeine? * What are the possible side effects of acetaminophen/butalbital/caffeine/codeine? * What other drugs will affect acetaminophen/butalbital/caffeine/codeine? * Where can I get more information? * What does my medication look like? Email this article Print this article What is the most important information I should know about acetaminophen/butalbital/caffeine/codeine? Do not stop taking acetaminophen/butalbital/caffeine/codeine suddenly if you have been taking it continuously for more than 5 to 7 days. Stopping suddenly could cause withdrawal symptoms and make you very uncomfortable. Your doctor may want to gradually reduce your dose. Codeine and butalbital will cause drowsiness and fatigue. Avoid alcohol, sleeping pills, antihistamines, sedatives, and tranquilizers except under the supervision of your doctor. These may also make you drowsy. Codeine will also cause constipation. Drink plenty of water (six to eight full glasses a day) to lessen this side effect. Increasing the amount of fiber in your diet can also help to alleviate constipation. Never take more acetaminophen/butalbital/caffeine/codeine than is prescribed for you. If your pain is not being adequately treated, talk to your doctor. Watch the acetaminophen content of other over-the-counter and prescription products while taking this medication. You should not exceed 4 grams (4000 mg) of acetaminophen per day. It is dangerous to drink alcohol while taking this medication. (back to top) What is acetaminophen/butalbital/caffeine/codeine? Codeine is in a class of drugs called narcotic analgesics. It relieves pain. Acetaminophen is a less potent pain reliever that increases the effects of codeine. Butalbital is in a class of drugs called barbiturates that slow down your central nervous system (brain and nerve impulses). Caffeine is believed to constrict dilated blood vessels that may contribute to tension headaches. Together, acetaminophen, butalbital, caffeine, and codeine are used to relieve complex tension headaches although precisely how it works is unknown. Acetaminophen/butalbital/caffeine/codeine may also be used for purposes other than those listed in this medication guide. (back to top) Who should not take acetaminophen/butalbital/caffeine/codeine? This medication is habit forming and should only be used under close supervision if you have an alcohol or drug addiction. Before taking this medication, tell your doctor if you have * kidney disease; * liver disease; * asthma; * urinary retention; * an enlarged prostate; * hypothyroidism; * seizures or epilepsy; * gallbladder disease; * a head injury; or * Addison's disease. You may not be able to take acetaminophen/butalbital/caffeine/codeine, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above. This drug combination is in the FDA pregnancy category C. This means that its effects on an unborn baby are not known. Do not take this medication without first talking to your doctor if you are pregnant. This drug combination passes into breast milk and may harm a nursing infant. Do not take this medication without first talking to your doctor if you are breast-feeding a baby. If you are younger than 18 years of age or older than 60 years of age, you may be more likely to experience side effects from this therapy. Use extra caution. Acetaminophen/butalbital/caffeine/codeine has not been approved for use in children younger than 12 years of age. (back to top) How should I take acetaminophen/butalbital/caffeine/codeine? Take acetaminophen/butalbital/caffeine/codeine exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you. Take each dose with a full glass of water. Take acetaminophen/butalbital/caffeine/codeine with food or milk if it upsets your stomach. Never take more of this medication than is prescribed for you. Too much acetaminophen/butalbital/caffeine/codeine could be very harmful. The maximum dose is six capsules per day. Do not stop taking acetaminophen/butalbital/caffeine/codeine suddenly if you have been taking it continuously for more than 5 to 7 days. Stopping suddenly could cause withdrawal symptoms and make you feel uncomfortable. Your doctor may want to gradually reduce your dose. Increase the amount of fiber and water (six to eight glasses daily) in your diet to prevent constipation. Do not share this medication with anyone else. Store acetaminophen/butalbital/caffeine/codeine at room temperature away from moisture and heat. (back to top) What happens if I miss a dose? Take the missed dose as soon as you remember. Do not take a double dose of this medication. Wait the prescribed amount of time before taking your next dose. (back to top) What happens if I overdose? Seek emergency medical attention. Symptoms of an acetaminophen/butalbital/caffeine/codeine overdose include slow breathing, seizures, dizziness, weakness, loss of consciousness, coma, confusion, tiredness, cold and clammy skin, small pupils, nausea, vomiting, and sweating. (back to top) What should I avoid while taking acetaminophen/butalbital/caffeine/codeine? Avoid alcohol while taking acetaminophen/butalbital/caffeine/codeine. Alcohol will greatly increase the drowsiness and dizziness caused by acetaminophen/butalbital/caffeine/codeine and could be dangerous. Also, acetaminophen can damage your liver if you drink three or more alcoholic beverages a day. Also avoid sleeping pills, tranquilizers, sedatives, and antihistamines except under the supervision of your doctor. These medications also may cause dangerous sedation. Use caution when driving, operating machinery, or performing other hazardous activities. Codeine and butalbital may cause drowsiness. If you experience drowsiness, avoid these activities. (back to top) What are the possible side effects of acetaminophen/butalbital/caffeine/codeine? If you experience any of the following serious side effects, stop taking acetaminophen/butalbital/caffeine/codeine and seek emergency medical attention: * an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives); * slow, weak breathing; * seizures; * cold, clammy skin; * severe weakness or dizziness; * unconsciousness; * yellowing of the skin or eyes; or * unusual fatigue, bleeding, or bruising. Other, less serious side effects may be more likely to occur. Continue to take acetaminophen/butalbital/caffeine/codeine and talk to your doctor if you experience * constipation; * dry mouth, nausea, vomiting, or decreased appetite; * dizziness, tiredness, or lightheadedness; * muscle twitches; * sweating; * itching; * decreased urination; or * decreased sex drive. Acetaminophen/butalbital/caffeine/codeine is habit forming. Do not stop taking it suddenly. Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. (back to top) What other drugs will affect acetaminophen/butalbital/caffeine/codeine? Do not take acetaminophen/butalbital/caffeine/codeine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. Dangerous side effects could result. The most serious interactions affecting acetaminophen/butalbital/caffeine/codeine are with those drugs that also cause sedation. The following drugs may lead to dangerous sedation if taken with acetaminophen/butalbital/caffeine/codeine: * antihistamines such as brompheniramine (Dimetane, Bromfed, others), diphenhydramine (Benadryl, Nytol, Compoz, others), chlorpheniramine (Chlor-Trimeton, Teldrin, others), and others; * tricyclic antidepressants, such as amitriptyline (Elavil) and doxepin (Sinequan), and serotonin reuptake inhibitors such as fluoxetine (Prozac), sertraline (Zoloft), and paroxetine (Paxil); * other commonly used antidepressants, including amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), imipramine (Tofranil), nortriptyline (Pamelor), and protriptyline (Vivactil); * anticholinergics such as belladonna (Donnatal), clidinium (Quarzan), dicyclomine (Bentyl, Antispas), hyoscyamine (Levsin, Anaspaz), ipratropium (Atrovent), propantheline (Pro-Banthine), and scopolamine (Transderm-Scop); * phenothiazines such as chlorpromazine (Thorazine), fluphenazine (Prolixin), thioridazine (Mellaril), and prochlorperazine (Compazine); and * tranquilizers and sedatives such as phenobarbital (Solfoton, Luminal), amobarbital (Amytal), secobarbital (Seconal), alprazolam (Xanax), diazepam (Valium), lorazepam (Ativan), flurazepam (Prosom), and temazepam (Restoril). Do not take any of the drugs listed above without the approval of your doctor. Many other drugs contain acetaminophen, especially over-the-counter pain, fever, cold, and allergy medications. Drugs other than those listed here may also interact with acetaminophen/butalbital/caffeine/codeine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines. (back to top) Where can I get more information? Your pharmacist has additional information about acetaminophen/butalbital/caffeine/codeine written for health professionals that you may read. (back to top) What does my medication look like? Acetaminophen/butalbital/caffeine/codeine is available with a prescription under the brand name Fioricet with Codeine. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you. Acetaminophen/butalbital/caffeine/codeine strengths are as follows: * Fioricet with Codeine 325 mg/50 mg/40 mg/ 30 mg--dark-blue/gray capsules (back to top) Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Copyright 1996-2003 Cerner Multum, Inc. Version: 5.04. Revision date: 2/13/04. 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